Glycemic index: history and clinical implications
One of the major dietary changes from the ancient to the modern world has been the increased consumption of fiber-depleted processed carbohydrate foods, coincident with rising rates of obesity and diabetes [8,9] and with great concern for increasing CHD risk. Pharmacological approaches to improve glycemic control in type 2 diabetes (T2DM) in large clinical trials have been shown useful but additional improvements in diabetes control have been demonstrated when diets of lower rather than higher GI are eaten [10e13]. Moreover, tight pharmacologic glycemic control has to date failed to show the anticipated clear benefits for CHD among T2DM patients, hence pharmacotherapy may represent only a partial solution.
Consensus statement
Dietary carbohydrates have received negative publicity in the last decade following the popularity of high protein diets.
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